The Hidden Epidemic: Sexually Transmitted Infections Among HIV Patients in Albania

Exploring the complex landscape of STIs among HIV patients in Albania, examining the latest research, uncovering barriers to effective care, and highlighting promising solutions taking root in Albanian communities.

HIV Epidemiology STI Prevention Public Health Albania Syndemic Approach

Introduction: A Dual Health Challenge in the Land of Eagles

Albania, a country known for its stunning Adriatic coastline and rugged mountain landscapes, is facing a less visible but increasingly concerning health challenge. While HIV prevalence remains relatively low compared to other European nations, the country is witnessing a troubling rise in new infections alongside persistent gaps in the management of sexually transmitted infections (STIs) among people living with HIV. This intersection of HIV and other STIs creates a perfect storm for public health, where each condition amplifies the impact of the other.

The synergistic relationship between HIV and other STIs is well-established in medical science. STIs can increase both the risk of HIV transmission and acquisition, while HIV can alter the presentation, progression, and treatment response of other STIs.

In Albania, where healthcare systems are evolving and stigma remains a significant barrier, this dual challenge demands urgent attention. As one executive director of an Albanian HIV association starkly warned, without improved prevention efforts, the goal of eliminating HIV by 2030 appears increasingly unattainable 1 .

Key Populations at Risk
  • Injecting drug users (IDUs)
  • Men who have sex with men (MSM)
  • Commercial sex workers
  • Roma population
Recent Trends
New HIV cases (first 10 months of 2024) 119
Incidence rate per 100,000 people 5
Regional ranking for HIV infection rate 1st
Cases among youth (15-29 years) ~22%

Albania's HIV Landscape: Between Progress and Persistent Challenges

The Current State of HIV in Albania

Albania finds itself at a crossroads in its HIV response. Historically considered a low-prevalence country, recent trends have raised concerns among public health experts. In the first ten months of 2024, 119 new HIV infections were identified, representing an incidence rate of 5 new cases per 100,000 people 1 . Perhaps more alarming is Albania's regional standing—the country now ranks first in the region for the highest HIV infection rate in the population 1 .

119

New HIV Cases (2024)

5

Per 100,000 Incidence

60%

Late Diagnosis

22%

Youth Cases (15-29)

HIV Statistics in Albania (2023-2024)
Indicator Figure Source
New HIV cases in first 10 months of 2024 119 1
Incidence rate per 100,000 people 5 1
Total cases diagnosed from 1993-2023 1,716 5
New cases in 2023 113 5
Cases among youth (15-29 years) ~22% of total 8

The STI and HIV Syndemic in Albania

The term "syndemic" describes the synergistic relationship between HIV and other STIs—each condition exacerbating the impact of the other. This phenomenon is particularly relevant in Albania, where limited public awareness and structural barriers to healthcare access create fertile ground for these interconnected health issues.

Research conducted among Albanian university students reveals significant gaps in comprehensive sexual health knowledge. While students showed better knowledge of STIs than their Italian counterparts in one study—with 20% of Albanians recognizing all STIs on a list compared to only 0.5% of students from Genoa and Lecce—knowledge remains unsatisfactory overall 2 . This knowledge gap, combined with behavioral risk factors, creates ideal conditions for the spread of both HIV and other STIs.

Changing Behavioral Patterns: Bio-behavioral surveillance studies have detected increases in risky behaviors, particularly among vulnerable sub-populations like injecting drug users, MSM, and those who have multiple and concurrent sexual partners 4 .

The Prevention Gap: A System Under Strain

The Impact of the Global Fund Exit

A critical turning point in Albania's HIV response came with the expiration of Global Fund support in December 2024. This departure had immediate practical consequences: all services supported by the Global Fund were halted, leading to a total lack of HIV tests and condoms for high-risk groups 1 . The Association of People Living with HIV reported a "complete shortage" of these essential prevention tools, forcing organizations to turn to neighboring countries for help 1 .

This funding crisis exposed the fragility of Albania's HIV prevention infrastructure. As one individual working with high-risk groups explained: "I have people coming to me saying they looked for PrEP but couldn't find it, and later they come back as HIV-positive individuals" 1 .

Challenges in HIV and STI Diagnosis and Linkage to Care

The cascade of HIV care in Albania reveals significant losses at each step of the journey from diagnosis to viral suppression. A 2016 study analyzing newly diagnosed cases found that out of 127 new HIV cases reported, only 100 (78.7%) entered care . Among those who entered care, 71% started antiretroviral therapy (ART), but viral load after initiation of ART was assessed in just 25 cases, with only 56% of patients achieving an undetectable HIV-RNA .

HIV Care Cascade in Albania (2016 Data)
Stage of Care Percentage of Patients Remaining Number
Total diagnosed 100% 127
Entered care 78.7% 100
Started ART 71% 71
Viral load assessed 35.2% 25
Achieved viral suppression 56% 14
Late Presentation Problem: Among those who started ART, 19.7% were late presenters and 54.9% were very late presenters . Late diagnosis not only leads to worse health outcomes for individuals but also increases the likelihood of HIV transmission to others.

A Closer Look: Investigating Knowledge and Barriers in Albanian Youth

Methodology of the Vlora University Study

To understand the barriers to HIV and STI prevention in Albania, let's examine a crucial 2018 study conducted at the University of Vlora. This cross-sectional investigation aimed to evaluate health beliefs and barriers related to HIV prevention and screening, with an emphasis on the association between voluntary counseling and testing (VCT) uptake and explanatory factors among university students 8 .

Study Design

The study employed a structured, self-administered questionnaire of the Knowledge, Attitude, Practice and Belief (KAPB) type, comprising four sections:

  1. Socio-demographic characteristics
  2. Perceptions related to health beliefs and barriers of screening methods
  3. Knowledge about preventive methods
  4. Sexual practices and VCT uptake
Sampling Method

The researchers used a multi-stage sampling technique:

  • Students stratified by field of study (health science vs. non-health science)
  • Departments selected using simple random sampling based on proportion
  • Students selected from each batch proportionally by simple random sampling

Sample: 710 participants with a mean age of 20.85 years 8 .

Key Findings and Implications

The Vlora study revealed several critical insights into the sexual health behaviors and perceptions of Albanian youth:

Barriers to HIV Prevention Identified in Vlora University Study (2018)
Barrier Category Specific Finding Percentage
Interpersonal Believe condom use insults partner 69%
Risk perception Would not avoid sex with multiple partners despite HIV risk 38%
Service utilization Sexually active students not using VCT services 78%
Geographic Rural students less likely to use HIV services 50% reduction

The study also identified striking differences between health science and non-health science students. Those from non-health sciences demonstrated lower utilization of HIV services, pointing to the protective effect of health education 8 .

These findings provide crucial insights for designing targeted interventions. The researchers concluded that "health beliefs and barriers are good predictors of the preventive behaviours toward HIV infection" and recommended creating awareness about HIV prevention, especially among non-health sciences students and those from rural areas 8 .
Educational Disparities

Students from non-health sciences demonstrated:

  • Lower utilization of HIV services
  • Poorer knowledge of prevention methods
  • Higher risk behaviors

Conclusion: Health education has a protective effect on sexual health behaviors.

The Path Forward: Promising Strategies and Innovations

Municipal Leadership and the Fast-Track Cities Initiative

Amidst the challenges, promising developments are emerging at the local level. Four Albanian cities—Kolonja, Durrës, Pogradec, and Shkodra—have signed the Paris Declaration on AIDS, committing to ending AIDS as a public health threat by 2030 5 . By joining this Fast-Track Cities initiative, these municipalities have committed to achieving the 95-95-95 targets by 2025 (90% of people living with HIV knowing their status, 90% on antiretroviral treatment, and 90% virally suppressed) 5 .

Recent Municipal Initiatives Against HIV/STIs in Albania
City Primary Focus Planned Interventions
Durrës Injecting drug users Expand methadone maintenance therapy by 10% annually 5
Pogradec & Kolonja Migrant populations Raise awareness to increase HIV testing rates 5
Shkodra Cross-border collaboration Partnership with Podgorica (Montenegro) for "Healthy Houses" model 5

Integrating STI and HIV Services

The interconnected nature of STIs and HIV demands integrated solutions. Research consistently shows that integrated service delivery improves health outcomes and represents a more efficient use of resources. For Albania, this might mean:

Co-testing for HIV and other STIs

During clinical encounters to maximize efficiency

Integrated prevention messaging

STI prevention messaging into HIV counseling

Comprehensive provider training

Training healthcare providers to address both HIV and STIs

Combined prevention packages

Include condoms, PrEP, and STI testing

Knowledge Gap: The need for such integration is underscored by research showing that Albanian university students have poor awareness of common STIs like HPV despite relatively better knowledge of HIV/AIDS 2 . This knowledge gap likely contributes to the continued transmission of both HIV and other STIs.

New Frontiers in Prevention and Treatment

Global research advances offer hope for strengthening Albania's response to HIV and STIs. Several innovations presented at recent international conferences could potentially benefit the Albanian context:

Long-acting prevention options

Twice-yearly lenacapavir for PrEP shows promising pharmacokinetic results, with a phase III trial planned 9 . Such long-acting options could overcome adherence challenges associated with daily PrEP.

Novel treatment regimens

Investigational once-weekly and twice-yearly treatment combinations could transform HIV management by reducing the burden of daily pill-taking 6 .

Doxycycline post-exposure prophylaxis

Real-world implementation has been associated with significant declines in bacterial sexually transmitted infections 9 .

These innovations, combined with strengthened health systems and reduced stigma, could significantly alter the trajectory of both HIV and STIs in Albania.

Conclusion: A Critical Juncture for Sexual Health in Albania

Albania stands at a pivotal moment in its response to sexually transmitted infections among HIV patients. The country faces significant challenges—from the withdrawal of international funding to persistent stigma and knowledge gaps—yet also possesses genuine opportunities for meaningful progress. The engagement of municipal governments, the potential for integrated service delivery, and advances in global research collectively offer a path forward.

The syndemic of HIV and STIs represents more than just a biomedical challenge; it reflects broader social, economic, and structural factors that influence health outcomes. As such, an effective response must extend beyond clinics and laboratories to address the underlying determinants of health, including education, stigma, and equitable access to services.

As Olimbi Hoxhaj, Executive Director of the Albanian Association of People Living with HIV, emphasized, the commitment of Albanian cities to the Fast-Track Cities initiative represents hope—not just for preventing new HIV infections but also for significantly reducing AIDS-related mortality 5 .

With determined leadership, evidence-based strategies, and community engagement, Albania can still turn the tide on these interconnected health challenges and move closer to making "Sexual Health for All" a reality rather than just an aspiration.

References